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Thread: MK-677 long term side effects?

  1. #1 12th July 2017 
    Piotr's Avatar
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    MK-677 long term side effects?

    My brother is going to the gym and wants to try some supplements. He is 19 years old.

    I am thinking about giving him some MK-677 but would like to ask if it has any adverse long term health effects? He would use it for 3 months then take a month off and repeat. I know that MK-677 can make you retain water and increase appetite but are there any harmful effects?

    Many thanks.
  2. #2 12th July 2017 
    stuplz's Avatar
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    I think that the only problem with MK-677 is high prolactin levels. While I haven't heard of many reports about high prolactin levels from MK-677, potentially they can get too high and I have also heard of cases where people developed gyno from MK-677. Symptoms of high prolactin levels are ED (Erectile dysfunction), gynecomastia, decreased muscle mass. I remember reading that someone had issues with achieving erection while using MK-677 but after coming off it returned to normal. Anyway, if your brother wants to be completely safe while using MK-677 then it might be a good idea to get some anti-prolactin drug like Cabergoline.
  3. #3 12th July 2017 
    Damme's Avatar
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    Yeah, the only think you should worry about is prolactin. But the prolactin becomes a problem usually on higher dosages. As your brother is still quite young then he would benefit from 10-15mg of MK-677, he doesn't need the usual 25mg's in my opinion. Also, the 10-15mg dose will give him good growth hormone increases with almost no side effects.

    I don't see the reason to take one month off after 3 months, he can take a few days off after some time but a month is not needed. MK-677 and other growth hormone secretagogues need to be used continuously for best effects, that on and off cycling will give you far fewer benefits.
  4. #4 14th July 2017 
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    Increased prolactin could cause a gynecomastia but as far as I know, MK-677 doesn't increase the prolactin levels to the point where you need to use anti prolactin drugs like caber or prami. If you use MK-677 at a maximum of 25mg's per day then it raises prolactin levels but within the normal range.

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