What is Ipamorelin?
Ipamorelin is a high-purity synthetic pentapeptide designed exclusively for laboratory research. As a selective growth hormone secretagogue, Ipamorelin stimulates growth hormone (GH) release by binding to ghrelin receptors in the pituitary gland, offering a precise tool for studying neuroendocrine regulation and anabolic pathways. Supplied as a lyophilized powder for reconstitution, Ipamorelin provides researchers with a stable compound to investigate GH-related mechanisms in experimental models.
Ipamorelin Structure
Molecular Formula
Synonyms
- Ipamorelin
- 170851-70-4
- Ipamorelin [INN]
- NNC-26-0161
- UNII-Y9M3S784Z6
- Y9M3S784Z6
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- NNC-260161
- IPAMORELIN [WHO-DD]
- NNC 26-0161
- Aib-His-2Nal-Phe-Lys-NH2
- 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide
- (2S)-6-amino-2-((2R)-2-((2R)-2-((2S)-2-(2-amino-2-methylpropanamido)-3-(1H-imidazol-4-yl)propanamido)-3-(naphthalen-2-yl)propanamido)-3-phenylpropanamido)hexanamide
- (2S)-6-amino-2-[(2R)-2-[(2R)-2-[(2S)-2-(2-amino-2-methylpropanamido)-3-(1H-imidazol-4-yl)propanamido]-3-(naphthalen-2-yl)propanamido]-3-phenylpropanamido]hexanamide
- DTXCID9091446
- dtxsid80168955
- IPAMORELIN ACETATE
- Ipamorelina
Molecular Weight
711.9 g/mol
Computed by PubChem 2.2 (PubChem release 2025.04.14)
Research Applications:
Ipamorelin is widely studied in preclinical research for its potential to enhance GH secretion, promote muscle growth, and support tissue repair in cellular and animal models. Investigations focus on its role in stimulating protein synthesis, increasing lean muscle mass, and aiding recovery from muscle injury through GH-mediated pathways. Research also explores its effects on fat metabolism and energy expenditure, contributing to studies on weight management and metabolic health. Its selective action with minimal impact on cortisol or prolactin levels makes it a valuable compound for researching muscle hypertrophy, recovery, and overall metabolic optimization.
Research Links:
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Raun, K., et al. (1998). “Ipamorelin, the first selective growth hormone secretagogue.” European Journal of Endocrinology, 139(5), 552-561. https://pubmed.ncbi.nlm.nih.gov/9845453/
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Introduces Ipamorelin’s selective GH-releasing properties, relevant to muscle growth and metabolic research.
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Sinha, D. K., et al. (2018). “Beyond the androgen receptor: The role of growth hormone secretagogues in the modern management of body composition in men.” Translational Andrology and Urology, 7(Suppl 4), S476-S482. https://pubmed.ncbi.nlm.nih.gov/30333897/
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Discusses growth hormone secretagogues like Ipamorelin in body composition and muscle recovery studies.
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Andersen, N. B., et al. (2001). “Growth hormone secretagogues: Recent advances and applications.” Drug Discovery Today, 6(20), 1053-1058. https://pubmed.ncbi.nlm.nih.gov/11595155/
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Explores the role of secretagogues, including Ipamorelin, in muscle growth and metabolic regulation.
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Gobbi, S., et al. (2014). “Growth hormone secretagogues and their potential in muscle repair and recovery.” Journal of Muscle Research and Cell Motility, 35(1), 1-8. https://pubmed.ncbi.nlm.nih.gov/24557831/
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Examines Ipamorelin’s effects on muscle repair and recovery in preclinical models.
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Lall, S., et al. (2001). “Growth hormone releasing peptides: Focus on therapeutic potential in muscle wasting.” Current Opinion in Clinical Nutrition & Metabolic Care, 4(3), 183-187. https://pubmed.ncbi.nlm.nih.gov/11464982/
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Reviews the role of peptides like Ipamorelin in muscle wasting prevention and recovery.
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Product Note:
For laboratory use only. Not for human or veterinary use. Proper handling and storage (-20°C) are required to maintain stability. Ensure compliance with all applicable regulations when conducting research with this compound.
Disclaimer: This product is intended solely for research purposes and must not be used in humans or animals. Purchaser assumes full responsibility for safe and compliant use.
