Research Peptides Peptide Guide

what are peptides

The first synthetic peptide

A peptide is a chemical compound containing two or more amino acids (amino acid polymers) that are coupled by a Peptides Bond . This bond is a special linkage in which the nitrogen atom of one amino acid binds to the carboxyl carbon atom of another.

Peptides are often classified according to the number of amino acid residues. Oligopeptides have 10 or fewer amino acids. Molecules consisting from 10 to 50 amino acids are called peptides. The term protein describes molecules with more than 50 amino acids.

Molecules with molecular weights ranging from several thousand to several million daltons (D) are called polypeptides. The terms polypeptide and protein are frequently used interchangeably.

In 1901, the first synthetic glycyl-glycine (see picture) was discovered by Emil Fischer, in collaboration with Ernest Fourneau. The first polypeptide (oxytocin - nine amino acid sequence) was synthesized by Vincent du Vigneaud in 1953.

Synthetic hormones have a wide range of applications in medicine and biotechnology. They regulate most physiological processes, acting at some sites as endocrine or paracrine signals and at others as neurotransmitters or growth factors.

Insulin was the first therapeutic protein to be introduced to treat insulin-dependent diabetes in the 1920s. There are sixty FDA approved peptide drugs in the market. About 140 these drugs are in clinical trials and over 500 are in pre-clinical development.

A number of these research chemicals are used for diagnostic purposes, for example C-peptide is used to monitor insulin production and to help determine the cause of low blood sugar (hypoglycemia).

These chemicals are synthesized by coupling the carboxyl group or C-terminus of one amino acid to the amino group or N-terminus of another. There are two strategies for synthetic hormone synthesis: liquid-phase synthesis and solid-phase synthesis (SPPS).

The goal of this project is to collect all information about peptides and their synthesis in one place.

Latest blog posts

Effectiveness of GHRH (CJC-1293, CJC-1295 DAC, MoD GRF 1-29)

Several studies involving CJC-1295 DAC have shown promising results regarding the increase of hGH (human Growth Hormone) in both men and women. The results were so good in fact that CJC-1295 DAC is pretty much the equivalent to Modified GRF 1-29. Here are some of the findings of the studies i...

Studies Show Online Peptide Retailers Donít Deliver What They Promise

Melanotan II products have been sold all over the internet to increase the skinís ability to tan for quite some time now. This product, which works by increasing brown-black eumelanin synthesis, darkens the skin when exposed to sunlight. It has also been nicknamed the Barbie-drug as a possible sid...

FDA and their view on Melanotan

Melanotan II has a lot of benefits, but for some reason the FDA still wonít put it on the market in the USA, because it causes skin cancer they say. Yes, the drug that is being used to prevent skin cancer in Europe is banned in the USA because, from their research perspective, it causes cancer. W...

The Actual Rules for the Use of Research Peptides (USA)

Yip, I contacted the FDA. It took ages to get the exact information I need, and Iím still waiting to hear back from the Medicines and Healthcare products Regulatory Agency in the UK for the full scope on the laws as they apply over thereÖ But for those of you who have been doing endless searches t...

New Delivery-Boy in Town

Science Daily recently posted an article about a brand new product that has been developed to deliver other drugs right into your cells. While the article and research is mostly aimed at combating disease and cancer I really think this little mister will benefit the bodybuilding scene as well. ...
Read All Articles

latest forum posts

  • dayana

    After using so many products finally get natural and useful serum for my dark circles. It ...

    dark circles under eyes

    06-25-2017 11:04 pm

  • firedan5415

    PM Cees. His guy has the low volume stuff....

    melanotan 2 not as strong as years befo

    06-25-2017 07:32 pm

  • Omallec

    Hey - the melanotan I got last year looked like the bottom vial. It was probably the best ...

    melanotan 2 not as strong as years befo

    06-25-2017 11:43 am

  • Omallec

    The person I usually buy melanotan from had a parcel stopped at customs coming from China....

    ordered melanotan from china

    06-25-2017 11:40 am

  • Omallec

    The only effects that I have had are moles becoming darker which lessons when the daily do...

    mt2 side effects

    06-25-2017 11:37 am

  • Omallec

    I've read people having varying degrees of success with nasal sprays. It's something I'd l...

    mt2 nasal spray

    06-25-2017 11:35 am

  • Hardy

    Hi all. My wife stumbled upon this site and passed it along to me and we're now both very...

    plan review

    06-24-2017 09:48 pm

  • KristenBrown

    I am noticing a difference in my darkness eye circles. I also love the way dermalmd under ...

    dark circles under eyes

    06-24-2017 12:08 pm

Latest created forum threads

Most commented forum threads