What is Epithalon?
Epithalon (also known as Epitalon) is a high-purity synthetic tetrapeptide designed exclusively for laboratory research. This peptide, structurally analogous to a segment of the pineal gland hormone epithalamin, is used to investigate telomerase activation, cellular aging, and regulatory mechanisms of the pineal gland. Supplied as a lyophilized powder for reconstitution, Epithalon provides researchers with a precise tool to study longevity and cellular homeostasis in experimental models.
Epithalon Structure

Source: Pubchem.
Molecular Formula
Synonyms
- Epitalon
- 307297-39-8
- Epithalon
- Glycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-
- Ala-Glu-Asp-Gly
Molecular Weight
390.35 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Dates
- Create: 2005-08-09
- Modify: 2025-05-24
Description
Epitalon is an organic molecular entity.
Source
Research Applications:
Epithalon is widely utilized in preclinical studies to explore its effects on telomere elongation and telomerase activity in cellular and animal models. Research focuses on its potential to influence gene expression related to aging, oxidative stress, and cellular senescence. Studies investigate its role in modulating melatonin production, circadian rhythms, and neuroendocrine balance, offering insights into mechanisms of age-related degeneration, DNA repair, and cellular proliferation. It is a key compound for research into longevity and age-associated physiological changes.
Product Note:
For laboratory use only. Not for human or veterinary use. Proper handling and storage (-20°C) are required to maintain stability. Ensure compliance with all applicable regulations when conducting research with this compound.
Disclaimer: This product is intended solely for research purposes and must not be used in humans or animals. Purchaser assumes full responsibility for safe and compliant use.