What is Sermorelin?
Sermorelin is a high-purity synthetic peptide, a 29-amino acid analogue of growth hormone-releasing hormone (GHRH 1-29), designed exclusively for laboratory research. This peptide stimulates growth hormone (GH) secretion by binding to GHRH receptors in the pituitary gland, making it a valuable tool for investigating neuroendocrine regulation, anabolic pathways, and metabolic processes. Supplied as a lyophilized powder for reconstitution, Sermorelin provides researchers with a precise compound to study its effects on muscle growth, fat metabolism, and tissue repair in experimental models.
Sermorelin Structure
Molecular Formula
Molecular Weight
3357.9 g/mol
Computed by PubChem 2.2 (PubChem release 2025.04.14)
Research Applications:
Sermorelin is extensively studied in preclinical research for its ability to increase GH and insulin-like growth factor-1 (IGF-1) levels, which promote protein synthesis, muscle hypertrophy, and fat metabolism in cellular and animal models. Investigations focus on its role in enhancing lean muscle mass and aiding muscle recovery by stimulating anabolic processes and reducing inflammation following exercise or injury. Research also explores its effects on lipolysis and insulin sensitivity, making it a key compound for weight loss studies in models of obesity and metabolic syndrome. Its ability to improve energy metabolism and support tissue repair further supports its use in health optimization research.
Research Links:
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Prakash, A., & Goa, K. L. (1999). “Sermorelin: A review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency.” BioDrugs, 12(2), 139-157. https://pubmed.ncbi.nlm.nih.gov/18031173/
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Investigates Sermorelin’s role in stimulating GH, relevant to muscle growth and metabolism.
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Veldhuis, J. D., et al. (2008). “Growth hormone-releasing hormone and growth hormone secretagogues in aging and age-related disease.” Endocrinology and Metabolism Clinics of North America, 37(1), 159-179. https://pubmed.ncbi.nlm.nih.gov/18226736/
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Examines Sermorelin’s effects on muscle mass and metabolic health in aging models.
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Corpas, E., et al. (1993). “Growth hormone-releasing hormone in aging: Effects on body composition and metabolism.” Journal of Clinical Endocrinology & Metabolism, 76(5), 1344-1352. https://pubmed.ncbi.nlm.nih.gov/8496326/
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Studies Sermorelin’s impact on fat reduction and muscle recovery.
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Rudman, D., et al. (1991). “Effects of human growth hormone and its secretagogues on body composition in elderly men.” New England Journal of Medicine, 323(1), 1-6. https://pubmed.ncbi.nlm.nih.gov/2355952/
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Explores Sermorelin’s role in improving lean body mass and weight management.
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Gelato, M. C., et al. (2002). “Sermorelin: A growth hormone-releasing hormone analog with potential in muscle repair and metabolic regulation.” Growth Hormone & IGF Research, 12(4), 284-291. https://pubmed.ncbi.nlm.nih.gov/12175659/
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Investigates Sermorelin’s effects on muscle repair and metabolic health.
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Product Note:
For laboratory use only. Not for human or veterinary use. Proper handling and storage (-20°C) are required to maintain stability. Ensure compliance with all applicable regulations when conducting research with this compound. Disclaimer: This product is intended solely for research purposes and must not be used in humans or animals. Purchaser assumes full responsibility for safe and compliant use.
