What is Teriparatide?
Teriparatide is a high-purity synthetic peptide, a 34-amino acid fragment of recombinant human parathyroid hormone (PTH 1-34), designed exclusively for laboratory research. This peptide acts as a potent agonist of the PTH/PTHrP receptor, making it a valuable tool for investigating bone metabolism, calcium homeostasis, and tissue repair pathways. Supplied as a lyophilized powder for reconstitution, Teriparatide provides researchers with a precise compound to study its effects on osteogenesis and metabolic regulation in experimental models.
Teriparatide Structure
Molecular Formula
Molecular Weight
6682 g/mol
Computed by PubChem 2.2 (PubChem release 2025.04.14)
Research Applications:
Teriparatide is extensively studied in preclinical research for its anabolic effects on bone and muscle tissue in cellular and animal models. Investigations focus on its ability to stimulate osteoblast activity, enhance bone formation, and improve muscle strength, which supports muscle recovery and overall health. Research also explores its potential to modulate energy metabolism and fat distribution, contributing to weight management studies by addressing metabolic dysfunction associated with bone loss or aging. Its role in promoting tissue repair and reducing inflammation makes Teriparatide a key compound for research into musculoskeletal health, recovery from injury, and metabolic optimization.
Research Links:
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Neer, R. M., et al. (2001). “Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.” New England Journal of Medicine, 344(19), 1434-1441. https://pubmed.ncbi.nlm.nih.gov/11346808/
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Investigates Teriparatide’s anabolic effects on bone, relevant to musculoskeletal health.
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Jilka, R. L., et al. (2009). “Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms.” Journal of Bone and Mineral Research, 24(11), 1860-1871. https://pubmed.ncbi.nlm.nih.gov/19419313/
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Examines Teriparatide’s role in bone formation, supporting muscle and skeletal recovery.
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Brixen, K. T., et al. (2004). “Effects of teriparatide on bone turnover markers and bone density in men with glucocorticoid-induced osteoporosis.” Journal of Clinical Endocrinology & Metabolism, 89(10), 5028-5034. https://pubmed.ncbi.nlm.nih.gov/15472199/
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Studies Teriparatide’s effects on bone and muscle health in metabolic contexts.
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Dempster, D. W., et al. (2011). “Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: A paired biopsy study.” Journal of Bone and Mineral Research, 26(9), 2069-2077. https://pubmed.ncbi.nlm.nih.gov/21541999/
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Explores Teriparatide’s impact on bone remodeling, with implications for muscle recovery.
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Sugimoto, T., et al. (2014). “Effects of teriparatide on muscle strength and physical function in postmenopausal women with osteoporosis.” Osteoporosis International, 25(5), 1431-1439. https://pubmed.ncbi.nlm.nih.gov/24322482/
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Investigates Teriparatide’s effects on muscle strength and recovery in aging models.
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Product Note:
For laboratory use only. Not for human or veterinary use. Proper handling and storage (-20°C) are required to maintain stability. Ensure compliance with all applicable regulations when conducting research with this compound.
Disclaimer: This product is intended solely for research purposes and must not be used in humans or animals. Purchaser assumes full responsibility for safe and compliant use.
